Astropharmacology — Part I —

Astropharmacology: name proposal for a scientific field devoted to study why names of magnificent planets are used as acronyms of poor quality clinical trials. Part 1: Neptune and Saturn — Study of Solifenacin Succinate and Tamsulosin Hydrochloride OCAS in Males With Lower Urinary Tract Symptoms (NEPTUNE) Why I think the overall quality of this study…

“Astropharmacology” name proposal for a scientific field devoted to study why names of magnificent planets are used as acronyms of poor quality clinical trials. Part 1: Neptune and Saturn

Study of Solifenacin Succinate and Tamsulosin Hydrochloride OCAS in Males With Lower Urinary Tract Symptoms (NEPTUNE) Why I think the overall quality of this study is poor? PubMed Commons comment on NEPTUNE A Study With Combination Treatment (Tamsulosin Hydrochloride and Solifenacin Succinate) in Male Patients With LUTS/BPH (SATURN) Why I think the overall quality of this…

Let’s compare models to predict WorldCup scores and disease outcomes. Part 1: “Eso era gol de Yepes”

WorldCup prediction model – Goldman Sachs: Open questions: 1. Do you think this prediction model is accurate? – The winner of the World Cup – The finalists and the score of the World Cup final – Team rankings (emphasis on 1st to 4th) 2. Would you be able to find the following information about this…

Meta-analysis provide the best strength of evidence about medical interventions: are you sure?

“Unchallenged, opinions became respected precedent then exceptionless concepts and sometimes even civil and academically accepted social law.” – Bucky Fuller I read this meta-analysis about agomelatine soon after it was published by the BMJ: Antidepressant efficacy of agomelatine: meta-analysis of published and unpublished studies Yesterday I submitted a rapid response (electronic letter to the BMJ…