Category: Unpublished Research

1, 2, 3: No sé.

— Los estudios no publicados incluyen ensayos clínicos Fase I/II realizados en humanos en donde se evalúan, entre otras variables, algunos parametros farmacocinéticos del fármaco o producto biológico experimental. Los estudios no publicados también incluyen estudios pre-clínicos (modelos animales, cultivos celulares, estudios en modelos de órgano aislado: farmacodinamia, toxicidad, metabolismo, entre otras). Existe un subreporte…

How many paroxetine studies registered at ClinicalTrials.gov remain unpublished over five years after their completion date?

I. Database:  ClinicalTrials.gov search query: paroxetine Studies completed before October 2010 (136 NCT Numbers) II. PubMed Search Query: 53 PubMed articles –> Matching 28 ClinicalTrials.gov records III. 108 paroxetine studies registered at ClinicalTrials.gov (completed before Oct 2010) –> No PubMed papers matching their corresponding NCT Number IV. Embase search query of 108 NCT Numbers not found…

1984 + 1 = 329

http://study329.org/timelines/ — Read also: http://davidhealy.org/study329-org-science-with-a-conscience/ “Although corporate malfeasance cases end up looking very big, they often have their origin in just… one or two people who didn’t quite do the right thing. It’s not about the big piece. The 100,000 people who work for GSK are just like you, right? I’m sure everybody who reads the BMJ…

Hi @pfizer,

How many closed studies sponsored by Pfizer remain unpublished? How many closed studies sponsored by Pfizer without disclosed results to ClinicalTrials.gov? https://clinicaltrials.gov/ct2/results/displayOpt?flds=a&flds=b&flds=c&submit_fld_opt=on&recr=Closed&lead=Pfizer&show_flds=Y — Pfizer se niega a transparentar datos obtenidos en ensayos clínicos http://t.co/C7qLx7TIn7 — Médicos Sin Marca (@MedicosSinMarca) September 1, 2015 .@Pfizer says greater clinical trial transparency offers no value to patients. They are…

Real world data about dabigatran (Pradaxa)

New real world data about dabigatran released by the FDA http://t.co/weeF1m2h3I — Boehringer (@Boehringer) May 15, 2014 — The evidence does not support Boehringer statements. Xian Ying, et al. Real world effectiveness of warfarin among ischemic stroke patients with atrial fibrillation: observational analysis from Patient-Centered Research into Outcomes Stroke Patients Prefer and Effectiveness Research (PROSPER) study 2015;…

“Return of Electro-Cures Exposes Psychiatry’s Weakness” – @sciam |HT @RsISK

“Transcranial magnetic stimulation is becoming an increasingly popular treatment for depression in spite of a lack of objective evidence of effectiveness. Illustration: National Institute of Mental Health.” The big promise & poor performance of electro-cures for the mind, by @Horganism With @DrDavidHealy on limits of ECT http://t.co/I15RSs3NR4 — Data Based Medicine (@RxISK) August 6, 2015 — Addendum:…

Phase 4 Interventional studies from Spain (completed before Jan 2011): How many unpublished?

Coauthored with Marc Casañas. Background: A few days ago we started to analyze data of public clinical trial registries with recruitment centers located in Spain. Analyzing hidden data of research is crucial to determine the influence of publication bias (cherry-picking), if the intended purpose is the correct scientific appraisal of the evidence about the effectiveness…

RIchmond Pharmacology Limited – #AllTrials

Shameful: Richmond Pharmacology launch judicial review to stop clinical trials transparency http://t.co/UE9xJODElq #AllTrials @senseaboutsci — Ben Ashby (@bnashby) May 19, 2015 PharmaGossip: A message from AllTrials about Richmond Pharmacology's Judicial Review: Dear AllTrials friendAs … http://t.co/TSg1HYnc0I — pharmagossip (@pharmagossip) June 12, 2015 — Richmond Pharmacology Limited – Database of Study Records https://t.co/sGtQ3sRZoH via @figshare https://t.co/1zUNmAM3wl — Jorge…