Category: Clinical Practice Guidelines

Phase 3 trials evaluating drugs & biologicals – studies located in Germany, UK, and France => ~ 50% unpublished

ClinicalTrials.gov search query (Nov 16, 2014): Closed Studies | Interventional Studies | Germany | United Kingdom | France | Phase 3 | received from 01/01/2002 to 01/01/2014 Results: 4496 studies – 67.2% of studies registered in Europe using the above search criteria View the updated map for this search query on ClinicalTrials.gov HOW TO ESTIMATE THE PERCENTAGE OF UNPUBLISHED…

Update: Data (i.e., evidence) about evidence based medicine.

Future updates:  http://chaoticpharmacology.com/hypothesis/ http://dx.doi.org/10.6084/m9.figshare.1093997   Update (Jan 8, 2014): Evidence Live 2015. April 14 and 15, Examination Schools Conference Centre, University of Oxford. “Evidence Live is a partnership between The BMJ and the Centre for Evidence-Based Medicine in the University of Oxford’s Nuffield Department of Primary Care Health Sciences.” – http://evidencelive.org/ The three submitted abstracts were…

Conflict of Interests: Clinical practice guideline (CPG) for the treatment of patients with acute coronary syndrome.

  “You’ll not receive further requests of retraction regarding the “Clinical practice guideline (CPG) for the treatment of patients with acute coronary syndrome. – (…) This will not be my last request of retraction of a clinical practice guideline authored by any of your organizations (i.e., Cinets Alliance and IETS).” 3rd request of #retraction: acute coronary syndrome…

Re: Global rules for global health: why we need an independent, impartial WHO

Response to (June 19, 2014):  Sridhar Devi, Frenk J, Gostin L, Moon S. Global rules for global health: why we need an independent, impartial WHO BMJ 2014; 348:g3841. Dear Editor, I read with interest the analysis published today by Sridhar and colleagues. I would like to make the following comments: – Over 50% of strong…

Fileset @figshare ‘Data (i.e., evidence) about evidence based medicine – http://shar.es/1XcAW8’: UPDATED | Related WordPress post

Original published Figure. Date of search query: July 3, 2014 Figure 1B — Updated. PubMed search query: Nov 20, 2014. Decreasing trends persist in both article types analyzed: evidence based medicine and practice guidelines. As usual, raw data & analysis are open. Please feel welcome to scrutinize & verify these numbers. Please tell me if you find any…

Polimedicación y medicación inapropiada – cc @antvillafaina @polimedlabs

Leer artículo completo en fisterra.com / Read the complete article on fisterra.com (article in Spanish) Gracias a Antonio Villafaina por compartir – polimedicado.org- Polimedicación y medicación inapropiada en fisterra http://t.co/AcPjr10mbU — antonio villafaina (@antvillafaina) November 18, 2014

Margaret McCartney: Have we given guidelines too much power? | BMJ 2014

Margareth McCartney: “Perhaps the problem is that we have given guidelines too much power, when we need professional, careful, individual judgment and discussion instead.” (1) – Re: agreed. Sincerely, Jorge H. Ramírez References McCartney Margaret. Margaret McCartney: Have we given guidelines too much power? BMJ 2014;349:g6027. http://dx.doi.org/10.1136/bmj.g6027