Clinical trials (research studies in people) can help find better treatment, care and prevention for patients. When done well, they answer important questions posed in the protocol (study plan) before the trial starts. Unfortunately, those answers are often not published. Some also don’t have the right study designs, which means the studies won’t tell us what we truly want to know.
…”the international Cochrane Collaboration commonly exclude from evidence 50% to 75% of published studies…”
– Soumerai, Starr, and Majumdar, The Health Care Blog
Why? They don’t meet the basic research design standards that Cochrane relies on to produce reliable results. 1/2 to 3/4 of our clinical trials? Big problem! But it’s only one of the issues.
Why Does This Happen?
Many misalignments help foster these problems. In their article, Soumerai et al show how clinical trialists start with errors that get multiplied as they gather steam, especially when those who will profit spin…
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